PCGSE-package {PCGSE}

Implementation of the Principal Component Gene Set Enrichment (PCGSE) and Spectral Gene Set Enrichment (SGSE) algorithms

Description

Contains logic to compute the statistical association between gene sets and the principal components of experimental data.

Details

Package:	PCGSE
Type:	Package
Version:	0.4.1
Date:	2023-08
License:	GPL-3

Principal component gene set enrichment is performed using the function pcgse. Spectral gene set enrichment is performed using the function sgse.

Note

This work was supported by the National Institutes of Health R01 grants LM010098, LM011360, EY022300, GM103506 and GM103534.

Author(s)

H. Robert Frost

References

• Frost, H. R., Li, Z., and Moore, J. H. (2014). Principal component gene set enrichment (PCGSE). ArXiv e-prints. arXiv:1403.5148.

• Frost, H. R., Li, Z., and Moore, J. H. (2014). Spectral gene set enrichment (SGSE). ArXiv e-prints.