calc_conditional_local_rejection_probs {OptimalGoldstandardDesigns}

Calculate the (local) conditional type I errors of both hypothesis given both interim test statistics.

Description

Calculate the (local) conditional type I errors of both hypothesis given both interim test statistics.

Usage

calc_conditional_local_rejection_probs(Z_TP1, Z_TC1, D, mu_vec = D$mu_vec$H0)

Arguments

Z_TP1

First stage Z-test statistic of the superiority test of treatment over placebo.

Z_TC1

First stage Z-test statistic of the non-inferiority test of treatment to the active control.

D

list containing all parameters of a the trial design.

mu_vec

vector of means of the test statistic c(Z_TP1, Z_TP2, Z_TC1, Z_TC1).

Value

named numeric vector with both conditional type I errors.