up.down {ORIClust}

up.down

Description

Returns the log-maximum likelihood and the estimator of the mean under under up-down profile with maximum at h.

Usage

up.down(data,x,n.rep,h)

Arguments

data

A vector containing the expressions of one gene.

x

A vector consisting of the average expression at time points (1, 2,... ,T), where T is the total number of time points.

n.rep

A vector consisting of the number of replicate arrays at time points (1, 2,... ,T), where T is the total number of time points.

h

Up-down profile with maximum at h.

Value

logelr

Log-maximum likelihood

mu

A vector containing the estimator of the mean

Author(s)

Tianqing Liu, Nan Lin, Ningzhong Shi and Baoxue Zhang

Maintainer: Tianqing Liu <[e-mail]>

References

Liu, T., Lin, N., Shi, N. and Zhang, B. (2009), Information criterion-based clustering with order-restricted candidate profiles in short time-course microarray experiments. BMC Bioinformatics, 10: 146.

Robertson, T., Wright, F. T. and Dykstra, R. L. (1988). Order restricted statistical inference. New York: Wiley.

Shi, N., Gao, W. and Zhang, B. (2001). One sided estimation and testing problems for location models from grouped samples. Commun Statist-Simula, 30: 885-898.