| MultEq-package {MultEq} | R Documentation |
Equivalence for multiple endpoints
Description
The package provides tests and confidence intervals for comparing two treatments when there is more than one primary response variable (endpoint). The step-up procedure of Quan et al. (2001) is both applied for differences and extended to ratios of means of normally distributed data with equal group variances. A related single-step procedure is also available.
Details
| Package: | MultEq |
| Type: | Package |
| Version: | 2.4 |
| Date: | 2022-03-02 |
| License: | GPL |
| LazyLoad: | yes |
multeq.diffEquivalence tests and related confidence intervals for differences of normal means of multiple endpoints
multeq.ratEquivalence tests and related confidence intervals for ratios of normal means of multiple endpoints
clinicData set of body measurements in a clinical study
Author(s)
Mario Hasler
Maintainer: Mario Hasler <hasler@email.uni-kiel.de>
References
Quan et al. (2001): Assessmant of equivalence on multiple endpoints, Statistics in Medicine 20, 3159-3173
Examples
data(clinic)
comp <- multeq.diff(data=clinic,grp="fact",method="step.up",margin.up=rep(0.6,5),
margin.lo=-rep(0.6,5))
summary(comp)