Metagenomics Longitudinal Differential Abundance Method


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Documentation for package ‘MetaLonDA’ version 1.1.8

Help Pages

areaPermutation Calculate Area Ratio (AR) of each feature's time interval for all permutations
curveFitting Fit longitudinal data
findSigInterval Find significant time intervals
intervalArea Calculate Area Ratio (AR) of each feature's time interval
metalonda Metagenomic Longitudinal Differential Abundance Analysis for one feature
metalondaAll Metagenomic Longitudinal Differential Abundance Analysis for all Features
metalonda_test_data Simulated data of OTU abundance for 2 phenotypes each has 5 subjects at 10 time-points
normalize Normalize count matrix
permutation Permute group labels
visualizeArea Visualize significant time interval
visualizeARHistogram Visualize Area Ratio (AR) empirical distribution
visualizeFeature Visualize Longitudinal Feature
visualizeFeatureSpline Visualize the feature trajectory with the fitted Splines
visualizeTimeIntervals Visualize all significant time intervals for all tested features
visualizeVolcanoPlot Visualize log2 fold-change and significance of each interval as volcano plot