Get_UV_from_beta {MTAR} | R Documentation |
Compute the summary statistics given the genetic effect estimates and their standard errors
Description
This function allows you to calculate the score summary statistics and their covariance matrix
for MTAR, given the genetic effect estimates and their standard errors
Usage
Get_UV_from_beta(Beta, Beta.se, R)
Arguments
Beta |
a numeric list, each sublist containing estimation information of genetic effect estimates |
Beta.se |
a numeric list, each sublist containing the standard error of estimators information for each study. In each study, a numeric |
R |
a SNP correlation matrix, which should contain the correlation of all the SNPs in these studies. |
Value
A list containing summary statistics for each traits, including the score summary statistics and their covariance matrix
.
Author(s)
Lan Luo
Examples
data("beta.example")
attach(beta.example)
obs.stat <- Get_UV_from_beta(Beta = Beta, Beta.se = Beta.se, R = R)
detach(beta.example)