MPBoost-package {MPBoost}

Treatment Allocation in Clinical Trials by the Maximal Procedure

Description

Performs treatment allocation in two-arm clinical trials by the maximal procedure described by Berger et al. (2003) <doi:10.1002/sim.1538>. To that end, the algorithm provided by Salama et al. (2008) <doi:10.1002/sim.3014> is implemented.

Details

Index of help topics:

MPBoost-package         Treatment Allocation in Clinical Trials by the
                        Maximal Procedure
mpboost                 Compute Allocation Sequences by the Maximal
                        Procedure

Author(s)

Ignacio López-de-Ullibarri

Maintainer: Ignacio López-de-Ullibarri <[e-mail]>

References

Berger, V. W., Ivanova, A., Knoll, M. D. (2003). Minimizing predictability while retaining balance through the use of less restrictive randomization procedures. Statistics in Medicine, 22: 3017-3028. doi:10.1002/sim.1538.

Salama, I., Ivanova, A., Qaqish, B. (2008). Efficient generation of constrained block allocation sequences. Statistics in Medicine, 27, 1421-1428. doi:10.1002/sim.3014.