cubeECHACR {MGDrivE}

Inheritance Cube: ECHACR

Description

This function creates an ECHACR construct, it has 5 alleles at the first locus and 4 alleles at the second.

• W: Wild-type

• H: Homing allele

• E: Eraser allele

• R: No-cost resistance allele

• B: Detrimental resistance allele

• cHW: Rate of homing from H, W -> H transition

• cEH: Rate of homing from E, H -> E transition

• cEW: Rate of homing from E, W -> E transition

Usage

cubeECHACR(
  cHW = 1,
  cEW = 1,
  cEH = 1,
  chHW = 0,
  crHW = 0,
  ceEW = 0,
  crEW = 0,
  ceEH = 0,
  crEH = 0,
  d1 = 0,
  d2 = 0,
  d3 = 0,
  eta = NULL,
  phi = NULL,
  omega = NULL,
  xiF = NULL,
  xiM = NULL,
  s = NULL
)

Arguments

cHW

Cutting efficiency of drive allele at locus 1

cEW

Cutting efficiency of ECHACR element into W

cEH

Cutting efficiency of ECHACR element into H

chHW

Homing efficiency of drive allele at locus 1

crHW

Resistance allele efficiency of drive allele at locus 1

ceEW

Homing efficiency of ECHACR element into W

crEW

Resistance allele efficiency of ECHACR element into W

ceEH

Homing efficiency of ECHACR element into H

crEH

Resistance allele efficiency of ECHACR element into H

d1

Background mutation rate from W into R allele

d2

Background mutation rate from H into R allele

d3

Background mutation rate from E into R allele

eta

Genotype-specific mating fitness

phi

Genotype-specific sex ratio at emergence

omega

Genotype-specific multiplicative modifier of adult mortality

xiF

Genotype-specific female pupatory success

xiM

Genotype-specific male pupatory success

s

Genotype-specific fractional reduction(increase) in fertility

Details

This inheritance pattern corresponds to the Active Genetic Neutralizing Elements for Halting or Deleting Gene Drives publication.

Value

Named list containing the inheritance cube, transition matrix, genotypes, wild-type allele, and all genotype-specific parameters.