IBS {MCPMod}

Irritable Bowel Syndrome Dose Response data

Description

A subset of the data used by (Biesheuvel and Hothorn, 2002). Except for the dose and the response variable all variables from the original data set are removed. The data are part of a dose ranging trial on a compound for the treatment of the irritable bowel syndrome with four active treatment arms, corresponding to doses 1,2,3,4 and placebo. Note that the original dose levels have been blinded in this data set for confidentiality. The primary endpoint was a baseline adjusted abdominal pain score with larger values corresponding to a better treatment effect. In total 369 patients completed the study, with nearly balanced allocation across the doses.

Usage

data(IBS)

Format

A data frame with 369 observations on the following 2 variables.

dose

a numeric vector

resp

a numeric vector

Source

Biesheuvel, E. and Hothorn, L. A. (2002). Many-to-one comparisons in stratified designs, Biometrical Journal, 44, 101–116