| poly3estf {MCPAN} | R Documentation |
Only for internal use.
Description
Poly-3- adjusted point and variance estimates for long term carcinogenicity data if data are given as a numeric time vector, a logical status vector and a factor containing a grouping variable
Usage
poly3estf(time, status, tmax=NULL, f, method = "BP", k=NULL)
Arguments
time |
a numeric vector of times of death of the individuals |
status |
a logical (or numeric, consisting of 0,1 only) vector giving the tumour status at time of death of each individual, where TRUE (1) = tumour present, FALSE (0) = no tumour present |
tmax |
a single numeric value, the time of sacrifice in the trial, or the last last time of death, defaults to the maximal value observed in time |
f |
a factor of the same length as time, status, giving the levels of a grouping variable in a one-way layout |
method |
a single charcter string, specifying the method for adjustment, with options: "BP" (Bailer Portier: assuming poly-3-adjusted rates are binomial variables), "BW" (Bieler, Williams: delta method as in Bieler-Williams (1993)) "ADD1" (as Bailer Portier, including an add1-adjustment on the raw tumour rates) "ADD2" (as Bailer Portier, including an add2-adjustment on the raw tumour rates following Agresti Caffo (2000) for binomials) |
k |
a single numeric value, the exponent to calculate survival adjusted proportions according to Bailer and Portier (1988), defaults to 3 |
Details
For internal use.
Value
A list containing:
Y |
a numeric vector, groupwise number of tumours |
n |
a numeric vector, groupwise number of individuals |
estimate |
a numeric vector, groupwise poly-3-adjusted rates according to Bailer, Portier (1988) |
weight |
a numeric vector of poly-3-adjusted weights |
estp |
a numeric vector, groupwise poly-3-adjusted rate (according to method) |
nadj |
adjusted n (sum of weights) |
varp |
a numeric vector, groupwise variance estimate (according to method) |
varcor |
a numeric vector, groupwise variance estimate, if necessary corrected such that estimates of 0 can not occur |
names |
a character vector, the levels of the grouping variable f |
k |
a single numeric value, as input |
Note
See poly3est
References
See poly3est
Examples
data(bronch)
poly3estf(status=bronch$Y, time=bronch$time, f=bronch$group, k=3)
poly3estf(status=bronch$Y, time=bronch$time, f=bronch$group, k=5)