hyalarthritis {MBNMAtime}

Studies comparing hyaluronan (HA)–based viscosupplements for osteoarthritis

Description

A dataset from of trials for pain reduction for patients with osteoarthritis treated with HA-based viscosupplements(Jansen et al. 2015). Data are reported in each study arm as mean change from baseline to follow-up on a visual analogue scale (0-100). The dataset includes 16 Randomised-Controlled Trials (RCTs), comparing 6 treatments and placebo.

Usage

hyalarthritis

Format

A data frame in long format (one row per arm and study), with 150 rows and 6 variables:

• studyID Study identifiers

• time Numeric data indicating the time at which the observation was measured (given in weeks)

• treatment Factor data indicating the treatment to which participants were randomised

• n Numeric data indicating the number of participants randomised to each arm

• y Numeric data indicating the mean change from baseline in HbA1c in a study arm

• se Numeric data indicating the standard error for the mean change from baseline in HbA1c in a study arm

Details

hyalarthritis is a data frame in long format (one row per observation, arm and study), with the variables studyID, time, treatment, n, y, and se.

References

Jansen JP, Vieira MC, Cope S (2015). “Network meta-analysis of longitudinal data using fractional polynomials.” Stat Med, 34(15), 2294-311. ISSN 1097-0258 (Electronic) 0277-6715 (Linking), doi:10.1002/sim.6492, https://pubmed.ncbi.nlm.nih.gov/25877808/.