Designing Multi-Arm Multi-Stage Studies

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Documentation for package ‘MAMS’ version 2.0.2

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MAMS-package Designing Multi-Arm Multi-Stage Studies
MAMS Designing Multi-Arm Multi-Stage Studies
mams Function to design multi-arm multi-stage studies with normal endpoints
mams.sim Simulating multi-arm multi-stage designs
MAMSNews Shows changes and news
new.bounds Function to update boundaries based on observed sample sizes
ordinal.mams Function to design multi-arm multi-stage studies with ordinal or binary endpoints
plot.MAMS Different generic functions for class MAMS.
plot.MAMS.stepdown Different generic functions for class MAMS.
print.MAMS Different generic functions for class MAMS.
print.MAMS.sim Different generic functions for class MAMS.
print.MAMS.stepdown Different generic functions for class MAMS.
stepdown.mams Function to find stopping boundaries for a 2- or 3-stage (step-down) multiple-comparisons-with-control test.
stepdown.update Update the stopping boundaries of multi-arm multi-stage study at an interim analysis, allowing for unplanned treatment selection and/or sample-size reassessment.
summary.MAMS Different generic functions for class MAMS.
summary.MAMS.sim Different generic functions for class MAMS.
summary.MAMS.stepdown Different generic functions for class MAMS.
tite.mams Function to design multi-arm multi-stage studies with time-to-event endpoints