LDcorSV-package {LDcorSV}

LDcorSV

Description

The package provides a set of functions which aim is to propose four measures of linkage disequilibrium: - Measure.R2: the usual r^2 measure.

- Measure.R2S: r^2 corrected by the structure of the sample (r^2_S).

- Measure.R2V: r^2 corrected by the relatedness of genotyped individuals (r^2_V).

- Measure.R2VS: r^2 corrected by both the relatedness of genotyped individuals and the structure of the sample (r^2_VS).

- LD.Measures: this function computes the four measures of linkage disequilibrium (r^2, r^2_V, r^2_S and r^2_{VS}) for a set of loci and gives extra information about them.

Author(s)

David Desrousseaux, Florian Sandron, Aurélie Siberchicot, Christine Cierco-Ayrolles and Brigitte Mangin

Maintainer: [e-mail]

References

Mangin, B., Siberchicot, A., Nicolas, S., Doligez, A., This, P., Cierco-Ayrolles, C. (2012). Novel measures of linkage disequilibrium that correct the bias due to population structure and relatedness. Heredity, 108 (3), 285-291. DOI: 10.1038/hdy.2011.73