Kalman Reaction Networks


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Documentation for package ‘Karen’ version 1.0

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get.cdn Get the cell differentiation network from a fitted Kalman Reaction Network.
get.fit Fit the state-space model to a clonal tracking dataset
get.sim.trajectories Simulate a clonal tracking dataset from a given cell differentiation network.
get.sMoments Get the first two-order smoothing moments from a fitted Kalman Reaction Network.
get.sMoments.avg Get the clone-average of the first two-order smoothing moments from a fitted Kalman Reaction Network.
nearestPD Nearest Positive Definite Matrix
Y_CT Clonal tracking data from clinical trials
Y_RM Rhesus Macaque clonal tracking dataset