Dream_Dataset {IntegratedMRF}

NCI-Dream Drug Sensitivity Prediction Challenge Dataset

Description

A demo dataset of different genomic characterizations and drug sensitivity selected from NCI-Dream Drug Sensitivity Prediction Challenge dataset.

Usage

Dream_Dataset

Format

A list of 6 variables containing genomic characterizations and drug sensitivity:

finalX_Dream

List of 5 Matrices where the matrices represent different genomic characterizations of Gene Expression, Methylation, RNA sequencing, Reverse Phase Protein Array (RPPA) and Copy Number Variation (CNV). 1000 predictor features for each subtype is included to satisfy package size limitations.

Cell_line_Index_Dream

List of Cell Line names for each genomic charcterization

finalY_train_Dream

Drug Sensitivity of training samples (35) for 31 drugs provided for NCI-Dream Drug Sensitivity Prediction Challenge

finalY_train_cell_Dream

Cell line names of the training samples

finalY_test_Dream

Drug Sensitivity of testing samples (18) for 31 drugs provided for NCI-Dream Drug Sensitivity Prediction Challenge Dataset

finalY_test_cell_Dream

Cell line names of the testing samples

Source

https://www.synapse.org/#!Synapse:syn2785778/wiki/70252

References

Costello, James C., et al. "A community effort to assess and improve drug sensitivity prediction algorithms." Nature biotechnology 32.12 (2014): 1202-1212.