ISOpureS2.model_optimize.cc.cc_loglikelihood {ISOpureR}

Compute the loglikelihood relevant to the patient cancer profiles, cc, for step 2

Description

Computes the part of the loglikelihood function relevant to optimizing cc for patient dd, the cancer profile for that patient

Usage

ISOpureS2.model_optimize.cc.cc_loglikelihood(ww, tumordata, dd, model)

Arguments

ww

the cc_weights for patient dd, with G entries

tumordata

a GxD matrix representing gene expression profiles of tumor samples

dd

the patient number

model

list containing all the parameters to be optimized

Value

The negative the part of the loglikelihood function relevant to optimizing cc for patient dd, the cancer profile for that patient.

Author(s)

Gerald Quon, Catalina Anghel, Francis Nguyen