ISOpureS1.model_optimize.omega.omega_compute_loglikelihood {ISOpureR}

Compute loglikelihood relevant to omega for step 1

Description

Computes the part of the loglikelihood function relevant to optimizing omega for step 1

Usage

ISOpureS1.model_optimize.omega.omega_compute_loglikelihood(omega, tumordata, model)

Arguments

omega

(K-1)x1 matrix representing the weights of the normal profiles B_i used to make the weighted combination that forms the mean parameter vector for the Dirichlet distribution over m

tumordata

a GxD matrix representing gene expression profiles of tumor samples

model

list containing all the parameters to be optimized

Value

The part of the loglikelihood function relevant to optimizing omega

Author(s)

Gerald Quon, Catalina Anghel, Francis Nguyen