ISOpureS1.model_optimize.kappa.kappa_compute_loglikelihood {ISOpureR}

Compute loglikelihood relevant to kappa for step 1

Description

Computes the part of the loglikelihood function relevant to optimizing kappa for step 1

Usage

ISOpureS1.model_optimize.kappa.kappa_compute_loglikelihood(kappa, tumordata, model) 

Arguments

kappa

a scalar kappa, the strength parameter in the prior over the reference cancer profile

tumordata

a GxD matrix representing gene expression profiles of tumour samples

model

list containing all the parameters to be optimized

Value

The part of the loglikelihood function relevant to optimizing kappa

Author(s)

Gerald Quon, Catalina Anghel, Francis Nguyen