SingleMiRNA_CRModel {IDMIR}

SingleMiRNA_CRModel

Description

Function "SingleMiRNA_CRModel" uses survival data to build a multivariate Cox model using the targets of a single miRNA.

Usage

SingleMiRNA_CRModel(ExpData,MiRNA,cutoff.point=NULL,SurvivalData)

Arguments

ExpData

A gene expression profile of interest (rows are genes, columns are samples).

MiRNA

A miRNA ID.

cutoff.point

A numeric value is used to divide high-risk and low-risk groups.

SurvivalData

Survival data (the column names are: "sample", "status", "time") corresponding to samples in the gene expression profile of interest.

Value

A list includes a data frame with seven parts those are "sample", "status", "time", "target genes expression", "risk score", "group", and a dataframe with five columns those are "Gene", "HR", "HR.95L", "HR.95H", "beta", and "P-value".

Examples

# Obtain the example data
GEP<-GetData_Mirna("GEP")
survival<-GetData_Mirna("survival")
# Run the function
SingleMiRNA_CRData<-SingleMiRNA_CRModel(GEP,
"hsa-miR-21-5p",cutoff.point=NULL,survival)