IdentifyMiRNA {IDMIR}

IdentifyMiRNA

Description

The function "IdentifyMiRNA" is used to identify significantly dysregulated miRNAs by calculating the eigenvector centrality of miRNAs.

Usage

IdentifyMiRNA(GDEscore.table,nperm=1000,damping=0.90)

Arguments

GDEscore.table

A matrix with one column of GDEscore.

nperm

The Number of random permutations (default: 100).

damping

Restart the probability of the random-walk algorithm (default: 0.9).

Value

A data frame with seven columns those are "MiRNA", "Target", "Number" (number of targets), "Score" (Centrality score), "P-value", and "FDR".

Examples

# Obtain the example data
GEP<-GetData_Mirna("GEP")
label<-GetData_Mirna("label")
# Run the function
GDEscore<-GetGDEscore(GEP,label)
MiRNAScore<-IdentifyMiRNA(GDEscore,nperm=5, damping=0.90)