ccData {ICODS}

Toy Example for Case-Cohort Design with Interval-Censored Data

Description

This data set gives a simple toy example of case-cohort design with interval-censored data. It was generated following the simulation study used to illustrate the method in the original manuscript referenced below. This dataset is not meaningful and is intended for demonstration purposes only.

Usage

data(ccData)

Format

A data.frame containing 500 observations with 6 columns:

U

examination time.

V

examination time.

del1

indicator of a left-censored observation I(T<=U).

del2

indicator of an interval-censored observation I(U<T<=V).

xi

indicating membership of the case-cohort sample.

z

covariates.

See Details for further information.

Details

The data can be understood as follow. There are K follow-up examinations at times TE = (T1, T2, ..., TK), and the failure time is denoted as TF. For left-censored data, the failure occurred prior to the first follow-up examination (TF < T1); therefore, U = T1, V = tau, and (del1,del2)=(1,0). For right-censored data, the failure had not yet occurred at the last follow-up examination (TF > TK); therefore, U = 0, V = TK, and (del1,del2)=(0,0). For interval-censored data, the failure occurred between two follow-up examinations, e.g. T2 < TF < T3; therefore, U and V to be the two consecutive follow-up examination times bracketing the failure time TF and (del1,del2)=(0,1).

References

Zhou, Q., Zhou, H., and Cai, J. (2017). Case-cohort studies with interval-censored failure time data. Biometrika, 104(1): 17–29. <doi:10.1093/biomet/asw067>