HWStrata {HardyWeinberg} | R Documentation |
Asymptotic test for HWE across strata for a single biallelic marker
Description
Function HWStrata
implements Olson's asymptotic test for HWE for a stratified sample of
single biallelic polymorphism.
Usage
HWStrata(X, verbose = TRUE)
Arguments
X |
A three-column matrix of genotype counts (e.g. with columns AA, AB, BB) |
verbose |
print output if |
Details
See the references for the related homogeneity assumption.
Value
T2 |
The test statistic |
pval |
The p-value |
Author(s)
Jan Graffelman jan.graffelman@upc.edu
References
Olson J.M. (1993) Testing the Hardy-Weinberg law across strata. Annals of Human Genetics 57(4):291-295.
Olson, J.M. and Foley, M. (1996) Testing for homogeneity of Hardy-Weinberg disequilibrium using data sampled from several populations. Biometrics 52(3) pp. 971-979.
See Also
Examples
#
# Test across strata
#
data("Glyoxalase")
Glyoxalase <- as.matrix(Glyoxalase)
HWStrata(Glyoxalase)
#
# Stratified exact testing, testing each sample
#
HWExactStats(Glyoxalase)
[Package HardyWeinberg version 1.7.8 Index]