HWClr {HardyWeinberg}

Compute the centred log-ratio transformation

Description

HWClr computes the centred log-ratio transformation for genotype counts of bi-allelic genetic markers.

Usage

HWClr(X, zeroadj = 0.5)

Arguments

X

A matrix of genotype counts (columns AA, AB and BB)

zeroadj

A zero adjustment parameter (0.5 by default)

Value

A matrix or vector of log-ratio coordinates

Author(s)

Jan Graffelman ([e-mail])

References

Graffelman, J. and Egozcue, J. J. (2011) Hardy-Weinberg equilibrium: a non-parametric compositional approach. In: Vera Pawlowsky-Glahn and Antonella Buccianti (eds.) Compositional Data Analysis: Theory and Applications, John Wiley & Sons, Ltd, pp. 207-215

See Also

HWAlr,HWIlr

Examples

   X <- HWData(100,100)
   Y <- HWClr(X)