GuoThompson8 {HWEintrinsic}

Guo and Thompson (1992) Eight Alleles Simulated Data

Description

A sample of size n = 30 of genotype frequencies from a population of r = 8 alleles simulated under the Hardy-Weinberg equilibrium when the underlying gene frequencies are (.2, .2, .2, .2, .05, .05, .05, .05); see Guo and Thompson (1992), Example 2.

Usage

data(GuoThompson8)

Format

An object of class HWEdata.

Source

Guo, S.W. and Thompson, E.A. (1992), "Performing the Exact Test of Hardy-Weinberg Proportion for Multiple Alleles". Biometrics, Vol. 48, No. 2, 361–372.

References

Consonni, G., Moreno, E., and Venturini, S. (2011). "Testing Hardy-Weinberg equilibrium: an objective Bayesian analysis". Statistics in Medicine, 30, 62–74. https://onlinelibrary.wiley.com/doi/10.1002/sim.4084/abstract

Examples

# Example 1 #
## Not run: 
# ATTENTION: the following code may take a long time to run! #


data(GuoThompson8)
plot(GuoThompson8)
n <- sum([e-mail], na.rm = TRUE)
out <- hwe.ibf.mc(GuoThompson8, t = n/2, M = 100000, verbose = TRUE)
summary(out, plot = TRUE)

## End(Not run)

# Example 2 #
## Not run: 
# ATTENTION: the following code may take a long time to run! #

M <- 300000
f <- seq(.1, 1, .05)
n <- sum([e-mail], na.rm = TRUE)
out <- hwe.ibf.plot(y = GuoThompson8, t.vec = round(f*n), M = M)

## End(Not run)