A Multiple Testing Procedure for High-Dimensional Mediation Hypotheses

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Documentation for package ‘HDMT’ version 1.0.5

• DESCRIPTION file.
• User guides, package vignettes and other documentation.

Help Pages

adjust_quantile	A function to compute the quantiles of the estimated mixture null distribution for pmax using either the approximation or exact method
correct_qqplot	A function to draw the corrected quantile-quantile plot for p-max using the expected quantiles
exercise_input	An example dataset to demonstrate the usage of 'HDMT'
fdr_est	A function to compute the estimated pointwise FDR for every observed p-max
fwer_est	A function used to compute Family wise error rate (FWER) cutoff for p-max at a designated level
null_estimation	A function to estimate the proportions of the three component nulls
snp_input	An example dataset to demonstrate the usage of 'HDMT'