ALShctObjects {HCT}

Objects Created by hct for the ALS of Clinical Trial Results

Description

These are objects of class hct for the example an ALS clinical trials

Format

Two hct objects hct220ALSFRS,hct220Delta. These are fit from the collection of ALS clinical trials without and with covariate predictions, respectively. They allow the use of the functions criteria and power functions to calculate statistics of interest, such as p-values for an historically controlled ALS trial

Examples

data(ALShctObjects)
#calculate the p-value of an ALS clinical trial where he
#slope of the ALSRS was -2 with standard Error 0.2
hct220ALSFRS$power(-.2,0,.2)
#Calculate the criteria for a p-value of 0.10 one sided to us in #a pilot study
hct220ALSFRS$criteria(0.1,.2)