| GWsignif-package {GWsignif} | R Documentation |
Estimating Genome-Wide Significance for Whole Genome Sequencing Studies, Either Single SNP Tests or Region-Based Tests
Description
The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.
Details
| Package: | GWsignif |
| Type: | Package |
| Version: | 1.2 |
| Date: | 2016-09-10 |
| License: | GLP 2.0 or greater |
Author(s)
ChangJiang Xu and Celia M.T. Greenwood Maintainer: ChangJiang Xu <changjiang.h.xu@gmail.com>
References
ChangJiang Xu, Ioanna Tachmazidou, Klaudia Walter, Antonio Ciampi, Eleftheria Zeggini, Celia M.T. Greenwood (2014) Estimating genome-wide significance for whole genome sequencing studies. Genetic Epidemiology
[Package GWsignif version 1.2 Index]