| Fluidigm {Fluidigm} | R Documentation |
Fluidigm
Description
Designed to streamline the process of analyzing genotyping data from Fluidigm machines, this package offers a suite of tools for data handling and analysis. It includes functions for converting Fluidigm data to format used by 'PLINK', estimating errors, calculating pairwise similarities, determining pairwise similarity loci, and generating a similarity matrix.
Title
Comprehensive Analysis of Fluidigm Genotyping Data
Description
A suite of tools designed to streamline the process of analyzing genotyping data from Fluidigm machines. It includes functions for converting Fluidigm data to 'PLINK' format, estimating errors, calculating pairwise similarities, determining pairwise similarity loci, and generating a similarity matrix.
Details
The package provides a comprehensive analysis pipeline for Fluidigm genotyping data. It starts by converting the raw data from the Fluidigm machine into a format that can be used with the 'PLINK' software. It then estimates errors in the data, calculates pairwise similarities between genotypes, determines pairwise similarity loci, and generates a similarity matrix. The package is designed to make it easier and more efficient for researchers to extract meaningful insights from their genotyping studies.
References
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, Bender D, Maller J, Sklar P, de Bakker PIW, Daly MJ & Sham PC (2007) PLINK: a toolset for whole-genome association and population-based linkage analysis. American Journal of Human Genetics, 81.
Purcell, Shaun. PLINK. https://zzz.bwh.harvard.edu/plink/
Author(s)
Maintainer: Daniel Fischer Daniel.Fischer@luke.fi (ORCID)
Authors:
Robert Ekblom (ORCID)
Other contributors:
Helena Johansson [contributor, funder]