protein_data {DrDimont}R Documentation

Protein data

Description

Protein analysis of breast cancer patients data from Krug et al. (2020) (data from the Clinical Proteomic Tumor Analysis Consortium (CPTAC)). The data is stratified by estrogen receptor (ER) expression status ('groupA' = ER+, 'groupB' = ER-). The data was reduced to 50 genes. For each group a data frame is given containing the raw data with the proteins as rows and the samples as columns. The first two columns contain the protein identifiers (ref_seq and gene_name).

Usage

protein_data

Format

groupA

ER+ data; data.frame: first two columns contain protein identifiers ref_seq and gene_name; other columns are samples containing the quantified proteomics data per protein

groupB

ER- data; data.frame: first two columns contain protein identifiers ref_seq and gene_name; other columns are samples containing the quantified proteomics data per protein

Source

Krug, Karsten et al. “Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy.” Cell vol. 183,5 (2020): 1436-1456.e31. doi:10.1016/j.cell.2020.10.036


[Package DrDimont version 0.1.4 Index]