| phosphosite_data {DrDimont} | R Documentation |
Phosphosite data
Description
Phosphosite analysis of breast cancer patients data from Krug et al. (2020) (data from the Clinical Proteomic Tumor Analysis Consortium (CPTAC)). The data is stratified by estrogen receptor (ER) expression status ('groupA' = ER+, 'groupB' = ER-). The data was reduced to 50 genes. For each group a data frame is given containing the raw data with the phosphosites as rows and the samples as columns. The first three columns contain the phosphosite and protein identifiers (site_id, ref_seq and gene_name).
Usage
phosphosite_data
Format
- groupA
ER+ data; data.frame: first three columns contain phosphosite and protein identifiers site_id, ref_seq and gene_name; other columns are samples containing the quantified phosphosite data per phosphosite
- groupB
ER- data; data.frame: first three columns contain phosphosite and protein identifiers site_id, ref_seq and gene_name; other columns are samples containing the quantified phosphosite data per phosphosite
Source
Krug, Karsten et al. “Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy.” Cell vol. 183,5 (2020): 1436-1456.e31. doi:10.1016/j.cell.2020.10.036