DYNATE {DYNATE}

DYNATE Function to conduct hierarchical mutiple testing based on the leaf p-values

Description

DYNATE Function to conduct hierarchical mutiple testing based on the leaf p-values

Usage

DYNATE(struct_map, L = 5, alpha = 0.05)

Arguments

struct_map

a data frame with both leaf information and P-value information.

L

maximum number of layers

alpha

desired FDR

Value

a data frame with testing results.

References

Li, Xuechan, Anthony Sung, and Jichun Xie. "Distance Assisted Recursive Testing." arXiv preprint arXiv:2103.11085 (2021). Pura, John, et al. "TEAM: A Multiple Testing Algorithm on the Aggregation Tree for Flow Cytometry Analysis." arXiv preprint arXiv:1906.07757 (2019).

Examples

data("p_leaf")

# Set tuning parameters
L <- 3 # layer number
alpha <- 0.05 # desired FDR

# conduct dynamic and hierarchical testing based on the leaf level p values.
out <- DYNATE(struct_map=p_leaf,L=L,alpha=alpha)
summary(out)