| simsolvd {DSBayes} | R Documentation |
Simulated SOLVD-Trial data set
Description
A simulated clinical trial based on the design of the Studies of Left Ventricular Dysfunction Trial (SOLVD-T), a placebo-controlled trial of the angiotensin-converting-enzyme inhibitor enalapril for patients with congestive heart failure.
Usage
data(simsolvd)Format
A data frame with 2569 observations on the following 12 variables.
- trt
indicator for enalapril group
- age
age at baseline (centered and scaled)
- beat
pulse at baseline (centered and scaled)
- lymphocyte
lymphocyte count at baseline (centered and scaled)
- lvef
left ventricular ejection fraction at baseline (centered and scaled)
- noise
simulated vector of random uniform variables
- nyha
indicator whether New York Heart Association score greater than 2
- cardratio
indicator whether cardiothoracic ratio is greater than 0.5
- creatinine
creatinine at baseline (centered and scaled)
- sodium
sodium at baseline (centered and scaled)
- ttodthorchfhosp
time to death or hospitalization in days
- censor
indicator whether censored (1) or an event (0)
- current
indicator whether current smoker
Source
Simulated data set based on the clinical study reported by: Yusuf, S. et al. (1991). Effect of Enalapril on Survival in Patients with Reduced Left-Ventricular Ejection Fractions and Congestive-Heart-Failure. NEJM 325:293-302.