Arterial {CrossCarry}R Documentation

Arterial pressure data of crossover design

Description

Data of a crossover experiment with three treatments to control arterial pressure: treatment A is a placebo, treatments B and C are 20 and 40 mg doses of a test drug. Thus, there were six three-period sequences: ABC, ACB, BCA, BAC, CAB and CBA, each one of them was applied to two individuals lasting six weeks each. Due to ethical reasons, there was no washout period between the treatments. In each period, 10 consecutive measurements of diastolic arterial pressure were taken: 30 and 15 minutes before, and 15, 30, 45, 60, 75, 90, 120 and 240 minutes after the administration of the treatment

Usage

Arterial

Format

A data frame with 360 rows and 5 columns:

Subject

The unique identifier of each of the patients

Period

The period of application of each treatment

Treatment

A is a placebo, treatments B and C are 20 and 40 mg doses of a test drug

Pressure

diastolic arterial pressure

Time

Measurement time

Source

Jones, B. and Kenward, M. G. (2015). Design and Analysis of Cross-Over Trials Third Edition. Chapman & Hall/CRC, Boca Raton


[Package CrossCarry version 0.2.0 Index]