arthritis {CopulaREMADA}R Documentation

The rheumatoid arthritis data

Description

Data obtained from a meta-analysis that aimed to determine whether anti-cyclic citrullinated peptide (anti-CCP) antibody identifies more accurately patients with rheumatoid arthritis than rheumatoid factor (RF) does. We include N=22 studies that assessed both RF and anti-CCP2 antibody for diagnosing rheumatoid arthritis.

Format

A data frame with 22 observations on the following 8 variables.

TP1

the number of true positives for RF

FN1

the number of false negatives for RF

FP1

the number of false positives for RF

TN1

the number of true negatives for RF

TP2

the number of true positives for anti-CCP2

FN2

the number of false negatives for anti-CCP2

FP2

the number of false positives for anti-CCP2

TN2

the number of true negatives for anti-CCP2

References

Nishimura, K., Sugiyama, D., Kogata, Y., et al. (2007) Meta-analysis: Diagnostic accuracy of anti-cyclic citrullinated peptide antibody and rheumatoid factor for rheumatoid arthritis. Annals of Internal Medicine, 146(11), 797–808.

Dimou, N.L., Adam, M. and Bagos, P.G. (2016) A multivariate method for meta-analysis and comparison of diagnostic tests. Statistics in Medicine, 35(20), 3509–3523.


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