AREDS {CopulaCenR}

AREDS

Description

A real dataset of bivariate interval-censored data with 629 subjects and 4 non-genetic covariates and 1 genetic covariate. The dataset is selected from the Age-related Eye Disease Study (AREDS) (AREDS Group, 1999). Two events are the progression times (in years) to late-AMD in the left and right eyes.

Usage

data("AREDS")

Format

A data frame with 1258 observations (629 subjects with 2 eyes) on the following 8 variables.

id

subject id

ind

margin indicator, 1=left eye, 2=right eye

Left

left bound of observed interval

Right

right bound of observed interval

status

censoring indicator; 1=interval-censor, 0=right censor.

SevScaleBL

baseline AMD severity score, margin-specific

ENROLLAGE

age at baseline

rs2284665

a SNP covariate highly associated with late-AMD progression, coded as 0,1,2

Source

AREDS Group (1999). The Age-Related Eye Disease Study (AREDS): design implications. AREDS report no. 1. Control Clinical Trials 20, 573-600.

Examples

data(AREDS)
copula2_sp <- ic_spTran_copula(data = AREDS,
              copula = "Copula2",
              var_list = c("ENROLLAGE",
                           "rs2284665",
                           "SevScaleBL"),
              l = 0, u = 15, m = 3, r = 3)
summary(copula2_sp)