computeN |
Estimation of Size and Numbers of Cases and Controls in the Target Population of Active Treatment Recipients At Risk at the Biomarker Sampling Timepoint |
computePower |
Power Calculations for Assessing Intermediate Biomarkers as Correlates of Risk in the Active Treatment Group in Clinical Efficacy Trials, Accounting for Biomarker's Measurement Error and Treatment Efficacy |
plotPowerCont |
Plotting of Power Curve versus Correlate of Risk Effect Size for Continuous Biomarkers |
plotPowerTri |
Plotting of Power versus Correlate of Risk Effect Size for Dichotomous and Trichotomous Biomarkers |
plotROCcurveTri |
Plotting of ROC Curves for Trichotomous Biomarkers |
plotRRgradVE |
Plotting of the Ratio of Relative Risks for Higher/Lower Latent Subgroups against Correlate of Risk Effect Size for Trichotomous Biomarkers |
plotVElatCont |
Plotting Treatment (Vaccine) Efficacy Curves for Different Correlate of Risk Relative Risks for Continuous Biomarkers |