MouseNeurons {ClusROC}

A subset of mouse brain cells data

Description

A subset of mouse brain cells data used in To el al. (2022). This is used to evaluate the ability of Lamp5 gene to discriminate three types of glutamatergic neurons. A full data is publicly available at https://portal.brain-map.org/atlases-and-data/rnaseq/mouse-v1-and-alm-smart-seq.

Usage

data(MouseNeurons)

Format

A data frame with 860 observations from 23 clusters and 7 variables:

sample_name

name of each observation.

subclass_label

a factor with 3 levels (types) of glutamatergic neurons, i.e., L2/3 IT (Layer 2/3 Intratelencephalic), L4 (Layer 4) and L5 PT (Layer 5 Pyramidal Tract) neurons.

genotype_id

the mouse genotype (which yield 23 clusters).

sex

the gender of mouse.

age_days

the age of mouse, in days.

Slc17a7_cpm

count per million of Slc17a7 (Solute Carrier Family 17 Member 7) gene expression.

Lamp5_cpm

count per million of Lamp5 (Lysosomal Associated Membrane Protein Family Member 5) gene expression.

References

To, D-K., Adimari, G., Chiogna, M. and Risso, D. (2022) “Receiver operating characteristic estimation and threshold selection criteria in three-class classification problems for clustered data”. Statistical Methods in Medical Research, 7, 31, 1325-1341.