nb {ClinicalUtilityRecal}

Net Benefit

Description

Estimates the net benefit and standardized net benefit of a risk score given a risk threshold R. Additionally estimates the standardized net benefit of a "treat-all" (everyone recieves intervention) treatment rule.

Usage

nb(y, p, r)

Arguments

y

Vector of binary outcomes, with 1 indicating event (case) and 0 indicating no event (controls)

p

Vector of risk score values

r

Clinically relevant risk threshold

Value

nb

Net benefit of risk score p

snb

Standardized net benefit of risk score p. Net benefit of p dived by the prevalence

snb.all

Standardized net benefit of a decision rule where everyone recieves treatment

Author(s)

Anu Mishra

References

Pauker, S. G., & Kassirer, J. P. (1980). The threshold approach to clinical decision making. New England Journal of Medicine, 302(20), 1109-1117.

Mishra, A. (2019). Methods for Risk Markers that Incorporate Clinical Utility (Doctoral dissertation). (Available Upon Request)