canopy.cluster.Estep {Canopy}

E-step of EM algorithm for multivariate clustering of SNAs

Description

E-step of EM algorithm for multivariate clustering of SNAs. Used in canopy.cluster.

Usage

    canopy.cluster.Estep(Tau, Mu, R, X)

Arguments

Tau

prior for proportions of mutation clusters

Mu

MAF centroid for each mutation cluster in each sample

R

alternative allele read depth matrix

X

total read depth matrix

Value

Matrix of posterior probability of cluster assignment for each mutation.

Author(s)

Yuchao Jiang [e-mail]

Examples

    data(AML43)
    R = AML43$R
    X = AML43$X
    Mu = AML43$Mu
    Tau = AML43$Tau
    pG = canopy.cluster.Estep(Tau, Mu, R, X)