canopy.cluster.Estep {Canopy} | R Documentation |

## E-step of EM algorithm for multivariate clustering of SNAs

### Description

E-step of EM algorithm for multivariate clustering of SNAs. Used in
`canopy.cluster`

.

### Usage

```
canopy.cluster.Estep(Tau, Mu, R, X)
```

### Arguments

`Tau` |
prior for proportions of mutation clusters |

`Mu` |
MAF centroid for each mutation cluster in each sample |

`R` |
alternative allele read depth matrix |

`X` |
total read depth matrix |

### Value

Matrix of posterior probability of cluster assignment for each mutation.

### Author(s)

Yuchao Jiang yuchaoj@wharton.upenn.edu

### Examples

```
data(AML43)
R = AML43$R
X = AML43$X
Mu = AML43$Mu
Tau = AML43$Tau
pG = canopy.cluster.Estep(Tau, Mu, R, X)
```

[Package

*Canopy*version 1.3.0 Index]