| nutrimouse {CCA} | R Documentation |
Nutrimouse dataset
Description
The nutrimouse dataset comes from a nutrition study
in the mouse. It was provided by Pascal Martin from
the Toxicology and Pharmacology Laboratory (French National
Institute for Agronomic Research).
Usage
data(nutrimouse)Format
A list containing the following components:
-
gene: data frame (40 * 120) with numerical variables -
lipid: data frame (40 * 21) with numerical variables -
diet: factor vector (40) -
genotype: factor vector (40)
Details
Two sets of variables were measured on 40 mice:
expressions of 120 genes potentially involved in nutritional problems.
concentrations of 21 hepatic fatty acids.
The 40 mice were distributed in a 2-factors experimental design (4 replicates):
Genotype (2-levels factor): wild-type and PPARalpha -/-
Diet (5-levels factor): Oils used for experimental diets preparation were corn and colza oils (50/50) for a reference diet (REF), hydrogenated coconut oil for a saturated fatty acid diet (COC), sunflower oil for an Omega6 fatty acid-rich diet (SUN), linseed oil for an Omega3-rich diet (LIN) and corn/colza/enriched fish oils for the FISH diet (43/43/14).
Source
P. Martin, H. Guillou, F. Lasserre, S. Déjean, A. Lan, J-M. Pascussi, M. San Cristobal, P. Legrand, P. Besse, T. Pineau - Novel aspects of PPARalpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study. Hepatology, in press, 2007.
References
www.inra.fr/internet/Centres/toulouse/pharmacologie/pharmaco-moleculaire/acceuil.html
Examples
data(nutrimouse)
boxplot(nutrimouse$lipid)