BeviMed-package {BeviMed}R Documentation

Bayesian Evaluation of Variant Involvement in Mendelian Disease


A fast integrative genetic association test for rare diseases.


BeviMed estimates a probability of association between a case/control label and allele counts at rare variant sites in a genomic locus and also, given that there is an association, the probabilities that each variant is involved in the disease. It does so by estimating the evidence for a model where the case/control label is independent of the allele configurations, and a model in which the probability of the case/control label depends on the corresponding allele configuration and a latent partition of variants into pathogenic and non-pathogenic groups.


Daniel Greene.

Maintainer: Daniel Greene <>


Greene et al., A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases, The American Journal of Human Genetics (2017),

See Also


[Package BeviMed version 5.8 Index]