f2calc {BayesDissolution} | R Documentation |
Calculation of the f2 Statistic
Description
This function calculates the f2 statistic as described in Moore and Flanner (1996).
Usage
f2calc(dis_data)
Arguments
dis_data |
A data frame containing the dissolution data. The first column of the data frame should denote
the group labels identifying whether a given dissolution belongs to the "reference" or "test" formulation group.
For a given dissolution run, the remaining columns of the data frame contains the individual run's dissolution
measurements sorted in time. Alternatively, the user may provide a data object of class dis_data containing the
dissolution data. See the |
Value
The function returns the f2 statistic calculated from the observed dissolution data.
Note
Use the plotdiss()
or ggplotdiss()
function to visually check if it's appropriate to calculate the f2 statistic.
References
Moore, J.W. and Flanner, H.H. (1996). Mathematical comparison of distribution profiles. Pharmaceutical Technology, 20(6):64-74.
Examples
### dis_data comes loaded with the package
f2calc(dis_data)