getCP {BIGL}

Estimate CP matrix from bootstraps

Description

This function is generally called from within fitSurface.

Usage

getCP(bootStraps, null_model, transforms, sigma0, doseGrid)

Arguments

bootStraps

the bootstraps carried out already

null_model

Specified null model for the expected response surface. Currently, allowed options are "loewe" for generalized Loewe model, "hsa" for Highest Single Agent model, "bliss" for Bliss additivity, and "loewe2" for the alternative Loewe generalization.

transforms

Transformation functions. If non-null, transforms is a list containing 5 elements, namely biological and power transformations along with their inverse functions and compositeArgs which is a list with argument values shared across the 4 functions. See vignette for more information.

sigma0

standard deviation of the null model on the real data

doseGrid

a grid of dose combinations

Value

Estimated CP matrix