be2x2 {BE} | R Documentation |
Bioequivalence test of a 2x2 study
Description
It performs conventional bioequivalence test for 2x2 study. Input is a file. Basic assumption is that the variable is distributed as a log-normal distribution. This is SAS PROC GLM style. If you want PROC MIXED style, use nlme::lme
.
Usage
be2x2(Data, Columns = c("AUClast", "Cmax", "Tmax"), rtfName="")
Arguments
Data |
A GRP : Group or Sequence, 'RT' or 'TR' PRD : Period, 1 or 2 SUBJ : Subject ID TRT : Treatment or Drug, 'R' or 'T' |
Columns |
Column names of variables to be tested. This is usaully c("AUClast", "Cmax", "Tmax") or c("AUClast", "AUCinf", "Cmax", "Tmax") |
rtfName |
Output filename of rich text format(rtf) |
Details
It performs bioequivalency tests for several variables of a 2x2 study in a data file. If you specify output filename in rtfName
, the output will be saved in the file.
Value
Returns text output of equivalence test result.
Author(s)
Kyun-Seop Bae <k@acr.kr>
See Also
Examples
be2x2(NCAResult4BE, c("AUClast", "Cmax", "Tmax"))