gene_s {BCT}R Documentation

SARS-CoV-2 gene S


This dataset contains the spike (S) gene, in positions 21,563–25,384 of the SARS-CoV-2 genome. The importance of this gene is that it codes for the surface glycoprotein whose function was identified in Yan et al. (2020) and Lan et al. (2020) as critical, in that it binds onto the Angiotensin Converting Enzyme 2 (ACE2) receptor on human epithelial cells, giving the virus access to the cell and thus facilitating the COVID-19 disease. The gene sequence is mapped to the alphabet 0,1,2,3 via the obvious map A->0, C->1, G->2, T->3.




An object of class "character".


Wu, F., S. Zhao, B. Yu, et al. (2020). A new coronavirus associated with human respiratory disease in China. Nature 579(7798), 265–269. (PMC)

Yan, R., Y. Zhang, Y. Li, L. Xia, Y. Guo, and Q. Zhou (2020). Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2. Science 367(6485), 1444–1448. (aaas)

Lan, J., J. Ge, J. Yu, et al. (2020). Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor. Nature 581, 215–220. (nature)


BCT(gene_s, 5)

[Package BCT version 1.2 Index]