GenPheno {AllelicSeries} | R Documentation |
Generate Phenotypes
Description
Generate Phenotypes
Usage
GenPheno(
anno,
beta,
covar,
geno,
reg_param,
binary = FALSE,
include_residual = TRUE,
indicator = FALSE,
method = "none",
prop_causal = 1,
random_signs = FALSE,
random_var = 0,
weights = c(0, 1, 2)
)
Arguments
anno |
(snps x 1) annotation vector. |
beta |
(3 x 1) coefficient vector for bmvs, dmvs, and ptvs respectively. |
covar |
Covariate matrix. |
geno |
(n x snps) genotype matrix. |
reg_param |
Regression parameters. |
binary |
Generate binary phenotype? Default: FALSE. |
include_residual |
Include residual? If FALSE, returns the expected value. Intended for testing. |
indicator |
Convert raw counts to indicators? Default: FALSE. |
method |
Genotype aggregation method. Default: "none". |
prop_causal |
Proportion of variants which are causal. |
random_signs |
Randomize signs? FALSE for burden-type genetic architecture, TRUE for SKAT-type. |
random_var |
Frailty variance in the case of random signs. Default: 0. |
weights |
Aggregation weights. |
Value
(n x 1) numeric vector.
[Package AllelicSeries version 0.0.4.1 Index]