cll_mutations {ActiveDriverWGS}R Documentation

CLL mutations

Description

CLL whole genome simple somatic mutations from Alexandrov et, 2013

Usage

data(cll_mutations)

Format

A data frame containing the following columns: chr, pos1, pos2, ref, alt, patient.

chr

autosomal chromosomes as chr1 to chr22 and sex chromosomes as chrX and chrY

pos1

the start position of the mutation in base 1 coordinates

pos2

the end position of the mutation in base 1 coordinates

ref

the reference allele as a string containing the bases A, T, C or G

alt

the alternate allele as a string containing the bases A, T, C or G

patient

the patient identifier as a string

Source

Publication

References

Alexandrov, Ludmil B., et al. "Signatures of mutational processes in human cancer." Nature 500.7463 (2013): 415. (PubMed)

Examples

data(cll_mutations)

data(cancer_genes)
ActiveDriverWGS(mutations = cll_mutations, elements = cancer_genes)


[Package ActiveDriverWGS version 1.1.2 Index]