LLL.SETTINGS {ASSISTant} | R Documentation |
A list of design and trial design settings used for analysis and simulations in the Lai, Lavori, Liao paper displayed in Tables 1 and 2. The elements of the list are the following
the sample size at each of three interim looks, the last being the final one; The length of this also determines the number of interim looks
the overall type I error
the fraction of type I error spent at each interim look
the type II error desired
A list of the 10 settings used in the simulations named S0
, S1
, ...,
S10
as in the paper, each with three elements
a 2\times J matrix of means, the first row for the null setting, the second for the alternative
a 2\times J matrix of standard deviations, the first row for the null setting, the second for the alternative
A list of two elements with prevalence vectors used in the paper; the lengths of these vectors implicitly define the number of groups.
a vector of equal prevalences for six groups used in table 1
a vector of prevalences used in table 2 of the paper
Adaptive Choice of Patient Subgroup for Comparing Two Treatments by Tze Leung Lai and Philip W. Lavori and Olivia Yueh-Wen Liao. Contemporary Clinical Trials, Vol. 39, No. 2, pp 191-200 (2014). http://www.sciencedirect.com/science/article/pii/S1551714414001311