LLL.SETTINGS {ASSISTant}  R Documentation 
Design and trial settings used in the Lai, Lavori, Liao paper simulations
Description
A list of design and trial design settings used for analysis and simulations in the Lai, Lavori, Liao paper displayed in Tables 1 and 2. The elements of the list are the following
 trialParameters

 N
the sample size at each of three interim looks, the last being the final one; The length of this also determines the number of interim looks
 type1Error
the overall type I error
 eps
the fraction of type I error spent at each interim look
 type2Error
the type II error desired
 scenarios

A list of the 10 settings used in the simulations named
S0
,S1
, ...,S10
as in the paper, each with three elements mean
a
2\times J
matrix of means, the first row for the null setting, the second for the alternative sd
a
2\times J
matrix of standard deviations, the first row for the null setting, the second for the alternative
 prevalences

A list of two elements with prevalence vectors used in the paper; the lengths of these vectors implicitly define the number of groups.
 table1
a vector of equal prevalences for six groups used in table 1
 table2
a vector of prevalences used in table 2 of the paper
References
Adaptive Choice of Patient Subgroup for Comparing Two Treatments by Tze Leung Lai and Philip W. Lavori and Olivia YuehWen Liao. Contemporary Clinical Trials, Vol. 39, No. 2, pp 191200 (2014, doi:10.1016/j.cct.2014.09.001).