TwoGrpCopriEndpt.SimPower {ADCT} | R Documentation |
Given the group sequential design information, returns the simulated overall power.
TwoGrpCopriEndpt.SimPower(mu11,mu12, mu21, mu22, rho, tau, alpha1, alpha2, alternative , Nmax, B)
mu11 |
standardized mean value for coprimary endpoint 1 in group 1. |
mu12 |
standardized mean value for coprimary endpoint 2 in group 1. |
mu21 |
standardized mean value for coprimary endpoint 1 in group 2. |
mu22 |
standardized mean value for coprimary endpoint 2 in group 2. |
rho |
correlation coefficient between two coprimary endpoints. |
tau |
information time for the interim analysis. |
alpha1 |
significant level for the first stage. |
alpha2 |
significant level for the second stage. |
alternative |
indicates the alternative hypothesis and must be one of |
Nmax |
maximum sample size per group. |
B |
the simulation iterative time. |
The evaluated power with attributes and computational error.
Yalin Zhu
Chang, M. (2014). Adaptive design theory and implementation using SAS and R. CRC Press.
# Example in Chang (2014) page 275 TwoGrpCopriEndpt.SimPower(mu11=0.2,mu12=0.25, mu21=0.005, mu22=0.015, rho=0.25, tau=0.5, alpha1=0.0025, alpha2=0.024, alternative = "two.sided",Nmax=584, B=10000)