CopriEndpt.Power {ADCT} | R Documentation |
Given the group sequential design information, returns the overall power.
CopriEndpt.Power(n, tau, mu1, mu2, rho, alpha1, alpha2, alternative)
n |
sample size for the design. |
tau |
information time for the interim analysis. |
mu1 |
mean value for coprimary endpoint 1. |
mu2 |
mean value for coprimary endpoint 2. |
rho |
correlation coefficient between two coprimary endpoints. |
alpha1 |
significant level for the first stage. |
alpha2 |
significant level for the second stage. |
alternative |
indicates the alternative hypothesis and must be one of |
The evaluated power with attributes and computational error.
Yalin Zhu
Chang, M. (2014). Adaptive design theory and implementation using SAS and R. CRC Press.
# Example in Chang (2014) page 272 CopriEndpt.Power(n=197, tau=0.5, mu1=0.2, mu2=0.2, rho=0.5, alpha1=0.0025, alpha2=0.024, alternative="one.sided") sapply(c(-0.8,-0.5,-0.2,0,0.2,0.5,0.8),CopriEndpt.Power, n=197, tau=0.5, mu1=0.2, mu2=0.2, alpha1=0.0025, alpha2=0.024, alternative="one.sided")